Drug Information

Drug General Information
Drug ID
D0C4NF
Former ID
DIB007472
Drug Name
FMP-825
Synonyms
FMP-825; Obesity therapeutics, MDI; Anti-obesity agent, MDI; Beta-3 adrenoceptor agonist, Molecular Design International; Beta-3 adrenoceptor agonists (obesity/diabetes); Beta-3 adrenoceptor agonists (obesity/diabetes), MDI
Indication Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] Investigative [543754]
Company
Molecular Design International Inc
Target and Pathway
Target(s) Beta-3 adrenergic receptor Target Info Agonist [543754]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Salivary secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 543754(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 30).
Ref 543754(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 30).

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