| Drug General Information |
| Drug ID |
D0A8QZ
|
| Former ID |
DIB002309
|
| Drug Name |
HDAC4 inhibtors
|
| Synonyms |
HDAC4 inhibtors (Huntington's disease)
|
| Indication |
Huntington's disease [ICD9: 294.1, 333.4; ICD10:F02.2, G10]
|
Investigative |
[1]
|
|---|
| Company |
CHDI Foundation Inc
|
| Target and Pathway |
| Target(s) |
Histone deacetylase 4 |
Target Info |
Modulator |
[1]
|
|---|
|
KEGG Pathway
|
Alcoholism
|
|
Epstein-Barr virus infection
|
|
Viral carcinogenesis
|
|
MicroRNAs in cancer
|
|
NetPath Pathway
|
IL2 Signaling Pathway
|
|
Pathway Interaction Database
|
Signaling events mediated by HDAC Class II
|
|
Signaling events mediated by HDAC Class III
|
|
Signaling events mediated by HDAC Class I
|
|
Sumoylation by RanBP2 regulates transcriptional repression
|
|
Validated nuclear estrogen receptor alpha network
|
|
Reactome
|
NOTCH1 Intracellular Domain Regulates Transcription
|
|
Constitutive Signaling by NOTCH1 PEST Domain Mutants
|
|
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
|
|
WikiPathways
|
Endochondral Ossification
|
|
Cardiac Hypertrophic Response
|
|
Neural Crest Differentiation
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
TarBasePathway
|
|
Cell Cycle
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
| References |
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2659). |
|---|
