Drug Information

Drug General Information
Drug ID
D07TXJ
Former ID
DCL000772
Drug Name
Dextofisopam
Synonyms
R-Tofisopam; Dextofisopam (USAN/INN); (5R)-1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
Drug Type
Small molecular drug
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Phase 2 [536224]
Company
Vela Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C22H26N2O4
Canonical SMILES
CCC1C(=NN=C(C2=CC(=C(C=C12)OC)OC)C3=CC(=C(C=C3)OC)OC)C
InChI
1S/C22H26N2O4/c1-7-15-13(2)23-24-22(14-8-9-18(25-3)19(10-14)26-4)17-12-21(28-6)20(27-5)11-16(15)17/h8-12,15H,7H2,1-6H3/t15-/m0/s1
InChIKey
RUJBDQSFYCKFAA-HNNXBMFYSA-N
CAS Number
CAS 82059-50-5
PubChem Compound ID
204105
PubChem Substance ID
10266076, 14804719, 14804722, 17397826, 30409347, 50169790, 57399411, 104438283, 129183163, 134339258, 135178646, 137010475, 142621282, 160698272, 198972132, 198990073, 223468661, 225069577, 226587837, 233628405
SuperDrug ATC ID
A10BG03
SuperDrug CAS ID
cas=111025468
Target and Pathway
Target(s) Peripheral-type benzodiazepine receptor Target Info Agonist [536224]
Gamma-aminobutyric acid receptor Target Info Agonist [536224]
KEGG Pathway Neuroactive ligand-receptor interaction
HTLV-I infection
References
Ref 536224Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.
Ref 536224Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.

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