Drug General Information
Drug ID	D03CFJ
Former ID	DIB002709
Drug Name	NCX-701
Synonyms	Nitroparacetamol; NO-acetaminophen, NicOx; NO-paracetamol, NicOx
Drug Type	Small molecular drug
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Discontinued in Phase 2	[547214]
Company	NicOx SA
Structure		Download 2D MOL 3D MOL
Formula	C12H14N2O6
Canonical SMILES	[N+](=O)([O-])OCCCC(=O)Oc1ccc(NC(=O)C)cc1
CAS Number	CAS 326850-30-0
PubChem Compound ID	6918532
Target and Pathway
Target(s)	Cyclooxygenase	Target Info	Modulator	[529064], [544102]
References
Ref 547214	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800014096)
Ref 529064	Nitroparacetamol (NCX-701) and pain: first in a series of novel analgesics. CNS Drug Rev. 2007 Fall;13(3):279-95.
Ref 544102	Antinociceptive effects of NCX-701 (nitro-paracetamol) in neuropathic rats: enhancement of antinociception by co-administration with gabapentin. Br J Pharmacol. 2009 September; 158(2): 601-609.

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