Drug Information
Drug General Information | |||||
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Drug ID |
D09NTC
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Former ID |
DNCL003453
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Drug Name |
CC-486
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Synonyms |
Nucleoside analogue
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Drug Type |
Small molecular drug
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Indication | Myelodysplastic syndrome [ICD9: 238.7; ICD10:D46] | Phase 3 | [549703] | ||
Company |
Celgene
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Structure |
Download2D MOL |
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Formula |
C19H20N4O
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Canonical SMILES |
CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O
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InChI |
1S/C19H20N4O/c1-22(2)12-13-6-8-14(9-7-13)18-21-16-5-3-4-15-17(16)23(18)11-10-20-19(15)24/h3-9H,10-12H2,1-2H3,(H,20,24)
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InChIKey |
SEKJSSBJKFLZIT-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
14801398, 24138480, 44938160, 49645682, 75980483, 99431558, 99460875, 103261452, 104015396, 104253502, 124757624, 124792817, 125164428, 136340148, 136920261, 137275824, 140105717, 152258354, 160647192, 162011827, 162037796, 162202721, 163908012, 164194027, 165247593, 172649965, 174528919, 178118772, 179551797, 185990463, 198960971, 223396135, 223704418, 231943732, 247394852, 249565774, 251962950, 252109983, 252214684, 252436436
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Target and Pathway | |||||
Target(s) | DNMT1 | Target Info | Inhibitor | [533326] | |
Pathway Interaction Database | Regulation of retinoblastoma protein | ||||
PathWhiz Pathway | Methionine Metabolism | ||||
References |
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