| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T33901 | ||||
| Target Name | Niemann-Pick C1-like protein 1 | ||||
| Target Type | Successful |
||||
| Drug Potency against Target | Ezetimibe-glucuronide | Drug Info | IC50 = 30 nM | [530100] | |
| References | |||||
| Ref 530100 | Bioorg Med Chem Lett. 2009 Jun 1;19(11):2965-8. Epub 2009 Apr 17.Spiroimidazolidinone NPC1L1 inhibitors. 1: Discovery by 3D-similarity-based virtual screening. | ||||
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