Target Validation Information
Target ID T46937
Target Name P2Y purinoceptor 12
Target Type
Successful
Drug Potency against Target PSB-0739 Drug Info Ki = 24.9 nM [530157]
PSB-0702 Drug Info Ki = 21 nM [530157]
References
Ref 530157J Med Chem. 2009 Jun 25;52(12):3784-93.High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.
Ref 530157J Med Chem. 2009 Jun 25;52(12):3784-93.High-affinity, non-nucleotide-derived competitive antagonists of platelet P2Y12 receptors.

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