Target expression details
| Target General Information | |||||
|---|---|---|---|---|---|
| Target ID | T00238 | ||||
| Target Name | mRNA of NF-kappa B | ||||
| Synonyms | DNAbinding factor KBF2 (mRNA); H2TF1 (mRNA); Lymphocyte translocation chromosome 10 protein (mRNA); Lyt10 (mRNA); NFKB2 (mRNA); Nuclear factor NFkappaB p100 subunit (mRNA); Nuclear factor NFkappaB p52 subunit (mRNA); Nuclear factor of kappa light polypeptide gene enhancer in Bcells 2 (mRNA); Oncogene Lyt10 (mRNA); NFKB2 | ||||
| Target Type | Clinical Trial | ||||
| Gene Name | NFKB2 | ||||
| Biochemical Class | Target of antisense drug | ||||
| UniProt ID | NFKB2_HUMAN | ||||
| Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
| Disease | Ulcerative colitis | ||||
| Example drug | DIMS-0150 | Phase 3 | [523735], [1572592] | ||
| Tissue | Colon mucosal tissue | ||||
| Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section | Fold-change: -0.01 Z-score: -0.03 P-value: 2.56E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of the persons with other diseases not directly affecting the tissue
Target gene expression profiles in the tissue of healthy individual
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| Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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