Target General Information
Target ID T00419
Target Name Skeletal muscle troponin C
Synonyms Beta-TnTF; Fast skeletal muscle troponin T; TNNI2; TNNT3; TnTf; Troponin C, skeletal muscle; Troponin I, fast skeletal muscle; Troponin I, fast-twitch isoform; Troponin T, fast skeletal muscle; fTnT; TNNC2
Target Type Clinical Trial
Gene Name TNNC2
Biochemical Class Troponin
UniProt ID TNNC2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Muscular atrophy
Example drug CK-2127107 Phase 1 [549466], [1572592]
Tissue Muscle tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.02
Z-score: 0.14
P-value: 3.79E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 549466Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800037810)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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