Target General Information
Target ID	T00938
Target Name	DHICA oxidase
Synonyms	5,6dihydroxyindole2carboxylic acid oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; TRP; TRP1; Tyrosinaserelated protein 1; TYRP1
Target Type	Clinical Trial
Gene Name	TYRP1
Biochemical Class	Tyrosinase
UniProt ID	TYRP1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Melanoma
Example drug	Flanvotumab			Phase 1	[523062], [1572592]
Tissue	Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.53 Z-score: 0.21 P-value: 7.82E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 523062	ClinicalTrials.gov (NCT01137006) An Open-Label, Dose-Escalation Study of IMC-20D7S In Patients With Malignant Melanoma. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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