Target General Information
Target ID	T01973
Target Name	Macrophage-stimulating protein receptor
Synonyms	CD136; CDw136; MSP receptor; Macrophagestimulating protein receptor; Macrophagestimulating protein receptor beta chain; Proteintyrosine kinase 8; p185Ron; MST1R
Target Type	Clinical Trial
Gene Name	MST1R
Biochemical Class	Kinase
UniProt ID	RON_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	MK-2461			Phase 1/2	[530708], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.03 Z-score: -0.23 P-value: 1.59E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 530708	MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor. Cancer Res. 2010 Feb 15;70(4):1524-33.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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