TTD | Expression Details

Target General Information
Target ID	T05938
Target Name	Mucin 16
Synonyms	CA125; Mucin16; Ovarian cancerrelated tumor marker CA125; Ovarian carcinoma antigen CA125; MUC16
Target Type	Clinical Trial
Gene Name	MUC16 {ECO:0000312\|HGNC:HGNC:15582}\|\|Synonyms=CA125 {ECO:0000303\|PubMed:11786729}
Biochemical Class	Mucin
UniProt ID	MUC16_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Ovarian cancer
Example drug	Oregovomab			Phase 3	[544415], [1572592]
Tissue	Ovarian tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 5.02 Z-score: 2.60 P-value: 4.86E-04
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: 1.61 Z-score: 0.70 P-value: 1.62E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data of the patients in the normal section of the tissue adjacent to the disease section Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 544415	MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress. Mol Cancer. 2014; 13: 129.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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