Target General Information
Target ID	T07063
Target Name	Sodium/iodide cotransporter
Synonyms	NIS; Na(+)/I(-) cotransporter; Na+/I-symporter; Sodium-iodide symporter; Sodium/iodide symporter; SLC5A5
Target Type	Clinical Trial
Gene Name	SLC5A5
Biochemical Class	Solute:sodium symporter
UniProt ID	SC5A5_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Prostate cancer
Example drug	Ad5CMV-NIS			Phase 1	[522479], [1572592]
Tissue	Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -1.48 Z-score: -1.37 P-value: 7.01E-04
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 522479	ClinicalTrials.gov (NCT00788307) Gene Therapy and Radioactive Iodine in Treating Patients With Locally Recurrent Prostate Cancer That Did Not Respond to External-Beam Radiation Therapy. U.S. NationalInstitutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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