Target General Information
Target ID	T07400
Target Name	Advanced glycosylation end product-specific receptor
Synonyms	RAGE; RAGESEC; Receptor foradvanced glycosylation end products; AGER
Target Type	Clinical Trial
Gene Name	AGER
Biochemical Class	Immunoglobulin
UniProt ID	RAGE_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	TTP-448			Phase 2	[550058], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 6.77E-03 Z-score: 0.04 P-value: 7.92E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 550058	Biopharmaceutical Research Companies are Developing Nearly 100 Medicines for Alzheimer's Disease and Other Dementias. Pharmaceutical Research and Manufacturers of America report. 2012.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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