Target General Information
Target ID	T12119
Target Name	Neuroendocrine sodium channel
Synonyms	Neuroendocrine sodium channel; Peripheral sodium channel 1; Sodium channel proteintype 9 subunit alpha; Sodium channel proteintype IX subunit alpha; hNE-Na; SCN9A
Target Type	Clinical Trial
Gene Name	SCN9A {ECO:0000312|HGNC:HGNC:10597}
Biochemical Class	Voltage-gated ion channel
UniProt ID	SCN9A_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	Corus 1030			Discontinued in Phase 2	[547604], [1572592]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.12 Z-score: -0.36 P-value: 1.42E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 547604	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017745)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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