Target General Information
Target ID T12646
Target Name Valosin-containing protein p97
Synonyms 15S Mg(2+)-ATPase p97 subunit; TER ATPase; Transitional endoplasmic reticulum ATPase; Valosin-containing protein; VCP
Target Type Clinical Trial
Gene Name VCP
Biochemical Class Acid anhydrides hydrolase
UniProt ID TERA_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Myeloma
Example drug CB-5083 Phase 1 [524919], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.88
Z-score: 3.55
P-value: 2.13E-05
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 524919ClinicalTrials.gov (NCT02243917) A Phase 1 Study Evaluating CB-5083 in Patients With Advanced Solid Tumors. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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