Target General Information
Target ID T15334
Target Name Cholesteryl ester transfer protein
Synonyms Cholesterol ester transfer protein; Lipid transfer protein I; CETP
Target Type Clinical Trial
Gene Name CETP {ECO:0000312|HGNC:HGNC:1869}
Biochemical Class Bactericidal permeability increasing protein
UniProt ID CETP_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Arteriosclerosis
Example drug DRL-17822 Phase 2 [523538], [1572592]
Tissue Peripheral blood
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.10
Z-score: -0.60
P-value: 8.86E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 523538ClinicalTrials.gov (NCT01388816) A Safety and Efficacy Study of DRL-17822, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Patients With Abnormal Cholesterol Levels. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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