Target expression details
Target General Information | |||||
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Target ID | T15334 | ||||
Target Name | Cholesteryl ester transfer protein | ||||
Synonyms | Cholesterol ester transfer protein; Lipid transfer protein I; CETP | ||||
Target Type | Clinical Trial | ||||
Gene Name | CETP {ECO:0000312|HGNC:HGNC:1869} | ||||
Biochemical Class | Bactericidal permeability increasing protein | ||||
UniProt ID | CETP_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Arteriosclerosis | ||||
Example drug | DRL-17822 | Phase 2 | [1], [2] | ||
Tissue | Peripheral blood | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.10 Z-score: -0.60 P-value: 8.86E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | ClinicalTrials.gov (NCT01388816) A Safety and Efficacy Study of DRL-17822, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Patients With Abnormal Cholesterol Levels. U.S. National Institutes of Health. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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