Target expression details

Target General Information
Target ID T15439
Target Name C5a anaphylatoxin chemotactic receptor
Synonyms C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; CD88; C5AR1
Target Type Clinical Trial
Gene Name C5AR1
Biochemical Class GPCR rhodopsin
UniProt ID C5AR1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Rheumatoid arthritis
Example drug NN8209 Discontinued in Phase 2 [548112], [1572592]
Tissue Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.19
Z-score: 0.77
P-value: 3.99E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Download target gene expression data of the patients in the disease section of the tissue
Download target gene expression data in the tissue of healthy individual
Disease Atopic dermatitis
Tissue Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.29
Z-score: 0.87
P-value: 2.34E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Download target gene expression data of the patients in the disease section of the tissue
Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref
Ref 548112Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022053)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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