Target General Information
Target ID	T15556
Target Name	Plasminogen activator inhibitor-1
Synonyms	Endothelial plasminogen activator inhibitor; PAI; PAI-1; Plasminogen activator inhibitor type 1; SERPINE1
Target Type	Clinical Trial
Gene Name	SERPINE1
Biochemical Class	Serpin family
UniProt ID	PAI1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	THR-18			Phase 2	[525337], [1572592]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.05 Z-score: 0.14 P-value: 1.56E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 525337	ClinicalTrials.gov (NCT02572336) A Study of the Safety, Imaging and Clinical Outcomes of THR-18 in Acute Stroke Subjects Treated With tPA.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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