Target General Information
Target ID T16128
Target Name Gastrin
Synonyms G14; G17; G34; G52; G6; Gastrin6; GAST
Target Type Clinical Trial
Gene Name GAST
Biochemical Class Gastrin cholecystokinin
UniProt ID GAST_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Gastric cancer
Example drug G17DT Phase 3 [524725], [1572592]
Tissue Gastric tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.93
Z-score: -0.75
P-value: 7.86E-01
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: -0.10
Z-score: -0.04
P-value: 4.25E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 524725ClinicalTrials.gov (NCT02118077) Sequential Trial of G17DT for the Treatment of Advanced Pancreatic Cancer. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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