Target General Information
Target ID	T16347
Target Name	Protein-tyrosine phosphatase 1B
Synonyms	PTP-1B; Tyrosine-protein phosphatase non-receptor type 1; PTPN1
Target Type	Clinical Trial
Gene Name	PTPN1
Biochemical Class	Phosphoric monoester hydrolases
UniProt ID	PTN1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Type 2 diabetes
Example drug	JTT-551			Terminated	[532867], [1572592]
Tissue	Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 7.21E-03 Z-score: 0.08 P-value: 9.44E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 532867	Pharmacological effects of JTT-551, a novel protein tyrosine phosphatase 1B inhibitor, in diet-induced obesity mice. J Diabetes Res. 2014;2014:680348.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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