Target General Information
Target ID T18299
Target Name CaM kinase II
Target Type Clinical Trial
Gene Name CAMK2A
Biochemical Class Kinase
UniProt ID KCC2A_HUMAN||KCC2B_HUMAN||KCC2D_HUMAN||KCC2G_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Rheumatoid arthritis
Example drug Rimacalib Phase 2 [544378], [1572592]
Tissue Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.33
Z-score: -0.93
P-value: 1.34E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 544378CaMKII inhibitors: from research tools to therapeutic agents. Front Pharmacol. 2014; 5: 21.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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