Target expression details
Target General Information | |||||
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Target ID | T18872 | ||||
Target Name | Malignant melanoma metastasis-suppressor KiSS-1 | ||||
Synonyms | KiSS-1; KISS1 | ||||
Target Type | Clinical Trial | ||||
Gene Name | KISS1 | ||||
Biochemical Class | Kisspeptin | ||||
UniProt ID | KISS1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Prostate cancer | ||||
Example drug | TAK-448 | Phase 2 | [1], [2] | ||
Tissue | Prostate | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.01 Z-score: -0.04 P-value: 6.40E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | ClinicalTrials.gov (NCT02381288) Effects of TAK-448 in Middle-aged and Older Men With Low Testosterone. U.S. National Institutes of Health. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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