Target General Information
Target ID T19579
Target Name Interleukin-2 receptor beta
Synonyms CD122; High affinity IL-2 receptor subunit beta; IL-2 receptor; P70-75; p75; IL2RB
Target Type Clinical Trial
Gene Name IL2RB
UniProt ID IL2RB_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Glioma
Example drug AFTVac Phase 2 [526997], [1572592]
Tissue Brainstem tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.06
Z-score: -1.11
P-value: 7.52E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Glioma
Example drug AFTVac Phase 2 [526997], [1572592]
Tissue White matter
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -4.70E-03
Z-score: -0.01
P-value: 1.96E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 526997Phase II randomized trial of autologous formalin-fixed tumor vaccine for postsurgical recurrence of hepatocellular carcinoma. Clin Cancer Res. 2004 Mar 1;10(5):1574-9.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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