Target expression details
Target General Information | |||||
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Target ID | T19760 | ||||
Target Name | Mixed lineage kinase 1 | ||||
Synonyms | Mixed lineage kinase 1; MAP3K9 | ||||
Target Type | Clinical Trial | ||||
Gene Name | MAP3K9 | ||||
Biochemical Class | Kinase | ||||
UniProt ID | M3K9_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | CEP1347 | Phase 2/3 | [1], [2] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.48 Z-score: 0.76 P-value: 9.49E-06 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Targeting the JNK signaling pathway for stroke and Parkinson's diseases therapy. Curr Drug Targets CNS Neurol Disord. 2005 Feb;4(1):63-7. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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