Target General Information
Target ID T21669
Target Name Glutathione S-transferase P
Synonyms GST classpi; GSTP11; GSTP1
Target Type Clinical Trial
Gene Name GSTP1
Biochemical Class Alkyl aryl transferase
UniProt ID GSTP1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Myelodysplastic syndromes
Example drug Ezatiostat Phase 2 [523599], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.42E-02
Z-score: 0.03
P-value: 4.46E-01
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: 1.28
Z-score: 3.26
P-value: 8.30E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 523599ClinicalTrials.gov (NCT01422486) Phase 2 Study of Telintra in Deletion 5q Myelodysplastic Syndrome. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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