Target General Information
Target ID	T22285
Target Name	Glutamate NMDA receptor subunit epsilon 1
Synonyms	HNR2A; N-methyl D-aspartate receptor subtype 2A; NMDA receptor NR2A; NMDAR2A; NR2A; GRIN2A
Target Type	Successful
Gene Name	GRIN2A
Biochemical Class	Glutamate-gated ion channel
UniProt ID	NMDE1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Parkinson's disease
Example drug	NBQX			Phase 1	[467600], [1572592]
Tissue	Substantia nigra tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.37 Z-score: -0.45 P-value: 8.43E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 467600	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4264).
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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