Target General Information
Target ID T22995
Target Name Hepcidin
Synonyms Hepc20; Hepc25; Hepcidin20; LEAP1; Liverexpressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor; HAMP
Target Type Clinical Trial
Gene Name HAMP
Biochemical Class Hepcidin family
UniProt ID HEPC_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Anemia
Example drug NOX-H94 Phase 2 [532202], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.18
Z-score: 0.47
P-value: 5.37E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 532202The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys. Blood. 2013 Mar 21;121(12):2311-5.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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