Target General Information
Target ID T29024
Target Name mRNA of SOD1
Synonyms mRNA of Superoxide dismutase 1; mRNA of Superoxide dismutase [Cu-Zn]; SOD1
Target Type Clinical Trial
Gene Name SOD1
Biochemical Class Oxidoreductases acting on superoxide as acceptor
UniProt ID SODC_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Lateral sclerosis
Example drug ISIS-SOD1 Phase 1 [551052], [1572592]
Tissue Cervical spinal cord
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.49
Z-score: -0.43
P-value: 2.51E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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