Target expression details
Target General Information | |||||
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Target ID | T29024 | ||||
Target Name | mRNA of SOD1 | ||||
Synonyms | mRNA of Superoxide dismutase 1; mRNA of Superoxide dismutase [Cu-Zn]; SOD1 | ||||
Target Type | Clinical Trial | ||||
Gene Name | SOD1 | ||||
Biochemical Class | Oxidoreductases acting on superoxide as acceptor | ||||
UniProt ID | SODC_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Lateral sclerosis | ||||
Example drug | ISIS-SOD1 | Phase 1 | [1], [2] | ||
Tissue | Cervical spinal cord | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.49 Z-score: -0.43 P-value: 2.51E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011). | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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