Target General Information
Target ID	T29754
Target Name	MAPKAP kinase 5
Synonyms	MAP kinaseactivated protein kinase 5; MAPKAP kinase 5; MAPKactivated protein kinase 5; MK5; PRAK; p38regulated/activated protein kinase; MAPKAPK5
Target Type	Discontinued
Gene Name	MAPKAPK5
Biochemical Class	Kinase
UniProt ID	MAPK5_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Rheumatoid arthritis
Example drug	GLPG-0259			Discontinued in Phase 2	[550825], [1572592]
Tissue	Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.87 Z-score: 1.37 P-value: 5.33E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 550825	Clinical pipeline report, company report or official report of Galapagos.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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