Target General Information
Target ID T30356
Target Name Blood group Rh(D) polypeptide
Synonyms CD240D; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; RHD
Target Type Clinical Trial
Gene Name RHD
Biochemical Class Ammonia transporter channel
UniProt ID RHD_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Anemia
Example drug Roledumab Phase 2/3 [524990], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.64
Z-score: 1.13
P-value: 4.18E-02
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 524990ClinicalTrials.gov (NCT02287896) Pharmacokinetics and Safety of Roledumab, in RhD-negative Pregnant Women Carrying an RhD-positive Foetus. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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