Target expression details
Target General Information | |||||
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Target ID | T30563 | ||||
Target Name | Leukotriene B4 receptor 2 | ||||
Synonyms | LTB4 receptor JULF2; LTB4-R2; Leukotriene B(4) receptor BLT2; Leukotriene B4 receptor BLT2; Seven transmembrane receptor BLTR2; LTB4R2 | ||||
Target Type | Discontinued | ||||
Gene Name | LTB4R2 | ||||
Biochemical Class | GPCR rhodopsin | ||||
UniProt ID | LT4R2_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Asthma | ||||
Example drug | LY-255283 | Terminated | [1], [2], [3] | ||
Tissue | Nasal and bronchial airway | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.04 Z-score: 0.15 P-value: 1.26E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3351). | ||||
REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001833) | ||||
REF 3 | NCBI GEO: archive for functional genomics data sets--update. |
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