Target expression details
Target General Information | |||||
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Target ID | T32240 | ||||
Target Name | Interleukin-15 | ||||
Synonyms | IL-15; IL15 | ||||
Target Type | Discontinued | ||||
Gene Name | IL15 | ||||
Biochemical Class | Cytokine: interleukin | ||||
UniProt ID | IL15_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Rheumatoid arthritis | ||||
Example drug | AMG-714 | Discontinued in Phase 1 | [1], [2] | ||
Tissue | Synovial tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.20 Z-score: 0.49 P-value: 2.95E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Emerging drugs for rheumatoid arthritis. Expert Opin Emerg Drugs. 2008 Mar;13(1):175-96. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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