Target General Information
Target ID	T32578
Target Name	Interleukin-6
Synonyms	B-cell stimulatory factor 2; BSF-2; CDF; CTL differentiation factor; Hybridoma growth factor; IL-6; Interferon beta-2; IL6
Target Type	Successful
Gene Name	IL6
Biochemical Class	Cytokine: interleukin
UniProt ID	IL6_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Rheumatoid arthritis
Example drug	CDP-6038			Phase 2	[1572592]
Tissue	Synovial tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 2.13 Z-score: 1.87 P-value: 1.49E-03
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Disease	Anemia
Tissue	Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.77 Z-score: -1.15 P-value: 8.08E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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