Target General Information
Target ID T34318
Target Name Cathelicidin antimicrobial peptide
Synonyms 18 kDa cationic antimicrobial protein; Antibacterial protein LL37; CAP18; Cathelicidin antimicrobial peptide; hCAP18; upregulating cAMP; CAMP
Target Type Successful
Gene Name CAMP {ECO:0000312|HGNC:HGNC:1472}
Biochemical Class Cathelicidin family
UniProt ID CAMP_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug Colforsin daropate hcl Approved [526492], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -9.06E-04
Z-score: -1.65E-03
P-value: 7.34E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 526492Cardiovascular and adenylate cyclase stimulating effects of colforsin daropate, a water-soluble forskolin derivative, compared with those of isoproterenol, dopamine and dobutamine. Circ J. 2002 Dec;66(12):1150-4.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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