Target General Information
Target ID	T35063
Target Name	GTP-binding protein GEM
Synonyms	GTPbinding mitogeninduced Tcell protein; GTPbinding protein GEM; RASlike protein KIR; GEM
Target Type	Clinical Trial
Gene Name	GEM
Biochemical Class	Small GTPase superfamily
UniProt ID	GEM_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Acute myelocytic leukemia
Example drug	Lirilumab			Phase 2	[525244], [1572592]
Tissue	Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.06 Z-score: 0.10 P-value: 4.29E-04
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 525244	ClinicalTrials.gov (NCT02481297) Lirilumab With Rituximab for Relapsed, Refractory or High-risk Untreated Chronic Lymphocytic Leukemia (CLL) Patients.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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