Target General Information
Target ID	T36935
Target Name	Prostate specific antigen
Synonyms	Gamma-seminoprotein; Kallikrein 3; P-30 antigen; PSA; Prostate-specific antigen; Semenogelase; Seminin; KLK3
Target Type	Clinical Trial
Gene Name	KLK3
Biochemical Class	Peptidase
UniProt ID	KLK3_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Prostate cancer
Example drug	Rilimogene galvacirepvec			Phase 3	[530657], [1572592]
Tissue	Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.04 Z-score: -0.09 P-value: 2.01E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 530657	Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol. 2010 Mar 1;28(7):1099-105.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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