Target General Information
Target ID T37735
Target Name Glutamate decarboxylase
Synonyms GS; Glutamateammonia ligase; Glutamine synthetase; GLUL
Target Type Discontinued
Gene Name GLUL
Biochemical Class Carbon-nitrogen ligase
UniProt ID GLNA_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Parkinson's disease
Example drug NLX-P101 Discontinued in Phase 2 [547621], [1572592]
Tissue Substantia nigra tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.23
Z-score: -0.40
P-value: 2.45E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 547621Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017938)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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