Target General Information
Target ID	T37952
Target Name	mRNA of SYK
Synonyms	Spleen tyrosine kinase (mRNA); Tyrosine-protein kinase SYK (mRNA); p72-Syk (mRNA); SYK
Target Type	Discontinued
Gene Name	SYK
Biochemical Class	Target of siRNA drug
UniProt ID	KSYK_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Asthma
Example drug	Syk kinase silencer			Discontinued in Phase 2	[1], [2]
Tissue	Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.29 Z-score: 0.43 P-value: 3.05E-05
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
REF 1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024464)
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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