Target General Information
Target ID T39123
Target Name G-protein coupled receptor 54
Synonyms GPR54; KiSS-1 receptor GPR54; KISS1R
Target Type Discontinued
Gene Name KISS1R
Biochemical Class GPCR rhodopsin
UniProt ID KISSR_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Prostate cancer
Example drug TAK-683 Discontinued in Phase 1 [548739], [1572592]
Tissue Prostate
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.74
Z-score: 0.91
P-value: 2.51E-03
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Reference
Ref 548739Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028256)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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