Target expression details
Target General Information | |||||
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Target ID | T40192 | ||||
Target Name | Nuclear factor kappa B p105 | ||||
Synonyms | DNAbinding factor KBF1; EBP1; Nuclear factor NFkappaB p105 subunit; Nuclear factor NFkappaB p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in Bcells 1; NFKB1 | ||||
Target Type | Clinical Trial | ||||
Gene Name | NFKB1 | ||||
UniProt ID | NFKB1_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Type 2 diabetes | ||||
Example drug | CAT 1004 | Phase 1 | [1], [2] | ||
Tissue | Liver tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.02 Z-score: 0.09 P-value: 6.21E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035050) | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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