Target General Information
Target ID T40192
Target Name Nuclear factor kappa B p105
Synonyms DNAbinding factor KBF1; EBP1; Nuclear factor NFkappaB p105 subunit; Nuclear factor NFkappaB p50 subunit; Nuclear factor of kappa light polypeptide gene enhancer in Bcells 1; NFKB1
Target Type Clinical Trial
Gene Name NFKB1
UniProt ID NFKB1_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug CAT 1004 Phase 1 [549312], [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.02
Z-score: 0.09
P-value: 6.21E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 549312Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035050)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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