Target General Information
Target ID	T40459
Target Name	Interleukin-13 receptor alpha-2
Synonyms	IL-13R alpha-2 chain; Interleukin-13 binding protein; IL13RA2
Target Type	Clinical Trial
Gene Name	IL13RA2
Biochemical Class	Cytokine receptor
UniProt ID	I13R2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Glioma
Example drug	ICT-107			Phase 2	[523325], [1572592]
Tissue	Brainstem tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 2.46 Z-score: 1.00 P-value: 4.40E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Disease	Glioma
Example drug	ICT-107			Phase 2	[523325], [1572592]
Tissue	White matter
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 4.14 Z-score: 2.11 P-value: 5.77E-05
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 523325	ClinicalTrials.gov (NCT01280552) A Study of ICT-107 Immunotherapy in Glioblastoma Multiforme (GBM). U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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