Target General Information
Target ID T42065
Target Name N-acetylmannosamine kinase
Synonyms Bifunctional UDPNacetylglucosamine 2epimerase/Nacetylmannosamine kinase; UDPGlcNAc2epimerase/ManAc kinase; GNE
Target Type Clinical Trial
Gene Name GNE
Biochemical Class Kinase
UniProt ID GLCNE_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Myopathy
Example drug GNE Lipoplex Phase 1 [549283], [1572592]
Tissue Muscle tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.02
Z-score: -0.04
P-value: 7.10E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 549283Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034673)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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