Target expression details
Target General Information | |||||
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Target ID | T42065 | ||||
Target Name | N-acetylmannosamine kinase | ||||
Synonyms | Bifunctional UDPNacetylglucosamine 2epimerase/Nacetylmannosamine kinase; UDPGlcNAc2epimerase/ManAc kinase; GNE | ||||
Target Type | Clinical Trial | ||||
Gene Name | GNE | ||||
Biochemical Class | Kinase | ||||
UniProt ID | GLCNE_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Myopathy | ||||
Example drug | GNE Lipoplex | Phase 1 | [1], [2] | ||
Tissue | Muscle tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.02 Z-score: -0.04 P-value: 7.10E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034673) | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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