Target expression details
Target General Information | |||||
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Target ID | T42928 | ||||
Target Name | Fibroblast growth factor 21 | ||||
Synonyms | Fibroblast growth factor 21; FGF21 | ||||
Target Type | Clinical Trial | ||||
Gene Name | FGF21 | ||||
Biochemical Class | Growth factor | ||||
UniProt ID | FGF21_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Type 2 diabetes | ||||
Example drug | PF-05231023 | Phase 1 | [1], [2] | ||
Tissue | Liver tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.05 Z-score: 0.22 P-value: 9.68E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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Reference | |||||
REF 1 | ClinicalTrials.gov (NCT01923389) Multiple Dose Study Of PF-05231023 In Obese Adult Subjects. U.S. National Institutes of Health. | ||||
REF 2 | NCBI GEO: archive for functional genomics data sets--update. |
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