Target General Information
Target ID T43115
Target Name Leukocyte common antigen
Synonyms CD45; CD45 antigen; L-CA; T200; PTPRC
Target Type Clinical Trial
Gene Name PTPRC
Biochemical Class Phosphoric monoester hydrolases
UniProt ID PTPRC_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Acute myelocytic leukemia
Example drug Iomab-B Phase 2 [546963], [1572592]
Tissue Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.26
Z-score: -0.36
P-value: 5.86E-05
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 546963Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800011613)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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