TTD | Expression Details

Target General Information
Target ID	T44682
Target Name	Interleukin-22
Synonyms	Cytokine Zcyto18; IL10related Tcellderivedinducible factor; ILTIF; Interleukin22; IL22
Target Type	Clinical Trial
Gene Name	IL22
Biochemical Class	Cytokine: interleukin
UniProt ID	IL22_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Psoriasis
Example drug	Fezakinumab			Phase 2	[524431], [1572592]
Tissue	Skin
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.07 Z-score: 0.23 P-value: 3.69E-03
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: 0.78 Z-score: 3.93 P-value: 3.51E-62
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data of the patients in the normal section of the tissue adjacent to the disease section Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 524431	ClinicalTrials.gov (NCT01941537) Randomized Placebo Controlled Study to Determine Safety, Pharmacodynamics and Efficacy of ILV-094 in Atopic Dermatitis. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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