Target General Information
Target ID	T45593
Target Name	Microtubule-associated protein tau
Synonyms	Neurofibrillary tangle protein; PHFtau; Paired helical filamenttau; MAPT
Target Type	Clinical Trial
Gene Name	MAPT
UniProt ID	TAU_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Alzheimer's disease
Example drug	LMT-X			Phase 3	[549271], [1572592]
Tissue	Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.22 Z-score: -0.60 P-value: 3.76E-06
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 549271	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034429)
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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