Target General Information
Target ID	T45612
Target Name	B7 homolog 3
Synonyms	4IgB7H3; B7 homolog 3; CD276 antigen; Costimulatory molecule; CD276
Target Type	Clinical Trial
Gene Name	CD276
Biochemical Class	Immunoglobulin
UniProt ID	CD276_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Glioma
Example drug	124I-8H9			Phase 1	[1], [2]
Tissue	White matter
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.53 Z-score: -1.33 P-value: 7.33E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Disease	Glioma
Example drug	124I-8H9			Phase 1	[1], [2]
Tissue	Brainstem tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.04 Z-score: -0.81 P-value: 3.92E-01
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Reference
REF 1	ClinicalTrials.gov (NCT01099644) Intraperitoneal Radioimmunotherapy With 131I-8H9 for Patients With Desmoplastic Small Round Cell Tumors and Other Solid Tumors Involving the Peritoneum. U.S. NationalInstitutes of Health.
REF 2	NCBI GEO: archive for functional genomics data sets--update.

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