Target General Information
Target ID T45968
Target Name RING finger protein 43
Synonyms RNF43
Target Type Clinical Trial
Gene Name RNF43
Biochemical Class Ligases (EC:6)
UniProt ID RNF43_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Rectal cancer
Example drug RNF43-721 Phase 2 [544256], [1572592]
Tissue Rectal colon tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 1.13
Z-score: 3.02
P-value: 2.79E-04
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section Fold-change: 1.19
Z-score: 5.66
P-value: 6.42E-08
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 544256Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer. Exp Ther Med. 2011 Jan-Feb; 2(1): 73-79.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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