Target General Information
Target ID	T46263
Target Name	Solute carrier family 3 member 2
Synonyms	4F2 cellsurface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; CD98; Lymphocyte activation antigen 4F2 large subunit; SLC3A2
Target Type	Clinical Trial
Gene Name	SLC3A2
Biochemical Class	RBAT transport accessory protein
UniProt ID	4F2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Acute myelocytic leukemia
Example drug	IGN523			Phase 1	[524608], [1572592]
Tissue	Bone marrow
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: 0.56 Z-score: 1.14 P-value: 3.68E-17
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 524608	ClinicalTrials.gov (NCT02040506) A Phase I Study of IGN523 in Subjects With Relapsed or Refractory AML. U.S. National Institutes of Health.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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